SSC CGL
MediumQ. No. which-organ-is-responsible-for-detoxification-of-blood
Which organ is responsible for detoxification of blood?
Last Updated:
AKidney
BSpleen
CLiver
DLymph node
Correct Answer: LiverYour Answer: C
✅ Correct Answer: C — Liver
The liver is the primary organ for detoxification in the human body. It filters all the blood from the digestive system before it circulates to the rest of the body. The liver breaks down (detoxifies) harmful substances including: drugs and medications (drug metabolism), alcohol (converted to acetaldehyde and then acetic acid), toxins (ammonia is converted to urea via the urea cycle), hormones, and metabolic waste products. Kupffer cells in the liver are specialized immune cells that destroy bacteria and foreign particles from the blood. The liver also produces bile for fat digestion, synthesizes clotting factors, and stores vitamins A, D, B12, and iron.
❌ Why other options are wrong:
• A. Kidney — The kidneys filter blood and remove metabolic waste (urea, creatinine) through urine. While kidneys do filter blood, they are NOT the primary organ for detoxification of toxins and drugs — that function belongs to the liver.
• B. Spleen — The spleen filters old, damaged red blood cells from the blood and plays an immune role. It does NOT detoxify drugs, alcohol, or chemical toxins.
• D. Lymph node — Lymph nodes filter lymph fluid and help fight infections by trapping pathogens. They are part of the lymphatic system and do NOT detoxify blood.
📝 Important Note: The liver is the largest gland in the human body (weighing about 1.5 kg). Key liver functions: Detoxification, Bile production (fat digestion), Glycogen storage, Protein synthesis (albumin, fibrinogen), Urea formation (from ammonia), Storage of vitamins (A, D, B12), and Fat metabolism. Hepatitis = liver inflammation. Cirrhosis = liver scarring (usually due to excess alcohol). Very important for SSC CGL Biology.
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